Description

(3beta,5alpha,11alpha,12beta,14beta,17alpha)-12-(Acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabinohexopyranosyl]oxy]-8,14-epoxy-11-(2-methyl-1-oxobutoxy)pregnan-20-one is a highly specialized, structurally complex steroidal glycoside derivative. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key intermediate or reference standard for novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis and study of bioactive natural products, cardiac glycosides, and other steroidal pharmaceuticals. The precise stereochemistry and functionalization make it a critical building block for targeted medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel steroidal drugs and bioactive molecules.
• Reference Standard: Used as a high-purity analytical standard for quality control, method development, and identification in pharmaceutical R&D and manufacturing.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents targeting various receptors.
• Natural Product Synthesis: Employed in the partial or total synthesis of complex natural products with cardiotonic or other biological activities.
• Biochemical Research: Used as a tool compound to investigate biological pathways and enzyme interactions involving steroidal structures.
• Process Development: Acts as a key intermediate for scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	(3beta,5alpha,11alpha,12beta,14beta,17alpha)-12-(Acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabinohexopyranosyl]oxy]-8,14-epoxy-11-(2-methyl-1-oxobutoxy)pregnan-20-one
CAS No.	191729-45-0
Molecular Formula	C44H68O14
Molecular Weight	821.00 g/mol
Synonyms	12-Acetyloxy-3-[(2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]-8,14-epoxy-11-(2-methyl-1-oxobutoxy)pregnan-20-one; 3-O-[(6-Deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)]-12β-acetoxy-11α-(2-methylbutyryloxy)-5β,14β-card-20(22)-enolide derivative; Steroidal glycoside intermediate; Cardiac glycoside analog; 191729-45-0; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

This high-value chemical is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from advanced techniques such as HPLC, NMR, and mass spectrometry. Our quality systems are designed to support cGMP and ISO standards for research and pharmaceutical applications, ensuring reliable data for regulatory submissions and process development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. The container should be kept in a dry, cool, and well-ventilated area. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.